Julie Ann Smith, DDS, MD;
Julie Ann Smith, DDS, MD
The reclassification of the Odontogenic Keratocyst (OKC) to the Keratocystic Odontogenic Tumor (KOT or KCOT) by the World Health Organization was done in part to reflect the aggressive nature of this lesion, but it was also based on new findings regarding the genetics of this lesion and its possible relationship to the function of the tumor suppressor gene, PTCH. The high recurrence rate of the KCOT has necessitated aggressive treatment. The spectrum of treatment previously offered to patients has included either aggressive resection or enucleation and curettage with either peripheral ostectomy, treatment with Carnoy’s solution, or cryotherapy. In recent years, marsupialization has proven to be a useful tool in shrinking these lesions, allowing the patient to avoid a more aggressive surgery. In the future, there may be a role for molecular based treatment. This course will focus on the clinical, radiographic, and pathologic diagnosis of this disease and the latest in management strategies.
At the conclusion of this course, the attendee will be able to describe the radiographic and clinical behavior of KCOT in the non-syndromic and syndromic patient, describe the pathologic findings in KCOT lesions, and be aware of the various treatment modalities, including their risks and general success rates.