Jorgen Slots, DDS, DMD, PhD, MS, MBA
Jørgen Slots, DDS, DMD, PhD, MS, MBA
New Approaches for Antimicrobial Treatment of Periodontal Disease
The recognition over the past three decades of microbial specificity in periodontitis has afforded dental practitioners the ability to prevent and treat the disease with a variety of antimicrobial drugs. These include systemic antibiotics, topical antibiotics and topical antiseptics. Systemic antibiotic therapy can be essential in eliminating pathogenic bacteria that invade gingival tissue and in helping control periodontal pathogens residing in various domains of the mouth from where they may translocate to periodontal sites. Frequently used periodontal combination antibiotic therapies are metronidazole-amoxicillin (250-375 mg of each/three times daily/8 days) and metronidazole-ciprofloxacin (500 mg of each/twice daily/8days). Microbiological analysis helps determine the optimal antibiotic therapy and the effectiveness of treatment. Topical antibiotics that are commercially available as controlled release devices suffer from several potential problems, including insufficient spectrum of antimicrobial activity in some periodontal polymicrobial infections, risks of producing an antibiotic resistant microbiota, and high acquisition costs. The presentation recommends periodontal treatment that includes a battery of professionally and patient administered antimicrobial agents. Available chemotherapeutics can provide effective, safe, practical and affordable means of controlling subgingival colonization of periodontal pathogens and various types of periodontal disease. Treatment protocols and patient cases will be presented.
At the conclusion of this course, attendees will have learned:
- Herpesviruses in periodontitis – treatment implications
- The type of periodontal patients who should be treated with adjunctive antimicrobial therapy
- Safe and effective antimicrobial therapies and how to select the most optimal antibiotic and antiseptic therapy for individual patients
- Effective and rational recall programs for periodontitis patients
- Super-effective, long-lasting and inexpensive means to combat bad breath and some types of tooth sensitivity (this part of the course is extremely valuable and the information is not being presented in other CE-courses in the USA)
Dr. Slots is a Professor of Periodontology and Microbiology at USC. He obtained DDS Denmark, and DMD and MBA from the University of Pennsylvania. He has served as the Chair of Oral Microbiology at the University of Goteborg, Sweden, and as the Chair of Periodontology and Associate Dean for Research at the USC. He is the Editor of three leading journals: Oral Microbiology and Immunology, Periodontology 2000 and Journal of Periodontal Research. He has published more than 300 articles and textbook chapters in periodontology, implantology and microbiology and has lectured extensively around the world.